Why That Stomach Ulcer Is Not Healing

There are several reasons why a stomach ulcer will not heal after weeks of full-dose drug therapy or recur rapidly after drug therapy is discontinued.

• Use of Non steroidal anti-inflammatory drugs (NSAIDs): NSAIDs are drugs that have analgesic and anti inflammatory actions. For example aspirin, ibuprofen, diclofenac, piroxicam etc.
• Persistent Helicobacter pylori (H pylori) infection.
• Over secretion of gastric acid.
• Other infectious diseases, such as herpes simplex, Cytomegalovirus infection, syphilis, and tuberculosis. 

The most common causes of recurrent ulcer or ulcer that won't go away however are: 

• Undiagnosed and persistent H pylori infection and 
• Careless NSAID use

The use of antibiotics, or proton pump inhibitors (PPIs- ulcer healing drugs) suppresses the H pylori bacterial load and may mask the diagnosis of an active H pylori infection in the stomach.

If you have a stomach ulcer or have been treated of an ulcer, talk to your doctor or pharmacist before going for over-the-counter analgesics to be sure you're taking the right one.

There are also some diseases that mimic peptic ulcers. So, if after treating, your symptoms are still there, do not repeat the drugs without going back to your doctor.

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